The leaves yield of volatile oil containing aldehyde sesquiterpenes, furfural, sulphur containing compounds and an alcohollochnerol. The plant contains amorhous alkaloidk, vincarosin. The anti-cancerdrugs, vincristine and vinblastine, are derived from the alkaloids of periwinkle.Alpasotis constituents are anthraglycosides ,cinnamic acid derivatives , mucins and pestins ,saponins ,amygdalin, ascaridol , geraniol,cymene , terpinine.
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